Cabergoline Regarding Dopamine

Cabergoline which is commonly known as Dostinex is a dopamine agonist. We like Dopamine.  Dopamine is good. Dopamine is a chemical, found in the brain, which transmits nerve impulses.  Dopamine is involved in the formation of epinephrine. This is probably why groups of Life-Extentionistas are very big on this Cabergoline. The hypothalamus releases dopamine, and that can inhibit the release of prolactin from the anterior lobe of the pituitary.  If you use anabolic steroids,  Cabergoline aka Dostinex aka Cabaser helps reduce the chance of any of prolactin related side-effects. Cabaser aka Cabergoline aka Dostinex has actually been shown in numerous studies to have an extremely high success rate in lowering prolactin and prolactin related conditions and side-effects.  In fact, for mgmt of hyperprolactinemia and it’s symptoms, Dostinex aka Cabergoline is the preferred treatment in terms of effectiveness as well as having very few undesirable side effects.  What does this mean for you? Cabergoline aka Dostinex does this very well for both men and women, it should be noted…almost identically actually.

More to come regarding cabergoline...

Dostinex Is Cabergoline

Cabergoline - Dostinex

The Technical Specs


Dostinex is a brand name.  Dostinex is one of the brand names for Cabergoline.

DOSTINEX Tablets contain cabergoline, which is the subject of this cabergoline blog and a dopamine receptor agonist. Cabergoline has a chemical name: 1-[(6-allylergolin-8ß-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea. Its empirical formula is C₂₆H₃₇N₅O₂, and its molecular weight is 451.62. The structural formula of cabergoline is as follows:

Cabergoline is a white powder soluble in ethyl alcohol, chloroform, and N, Ndimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water.

DOSTINEX Tablets, for oral administration, contain 0.5 mg of cabergoline. Inactive ingredients consist of leucine, USP, and lactose, NF.

Cabergoline can also come as liquid cabergoline.  You won't see a liquid Dostinex because Dostinex is a brand of cabergoline and they only make it in tablets.

The following paragraphs regarding Dostinex aka cabergoline are from http://www.isteroids.com/steroids/Dostinex-Cabergoline.html Dostinex was originally introduced to the bodybuilding community by the anti-aging crowd. About a decade ago, the only place you could really find this stuff being sold was on mail order lists for various life-extension clinics. Although they are, frankly, a very weird bunch of people, the life-extensionistas were among the first to find and make available a lot of the stuff that eventually found its way into athletic circles, like Dostinex and other such nootropics (drugs that increase mental activity).

Dostinex is one of those drugs. I first saw it on an anti-aging clinic’s price list about a decade ago, and more recently, I saw it being discussed by various people who are “in the know” on the internet. The former fact made it slightly interesting to me, while the latter had exactly the opposite effect. Actually, I first mentioned it in an ancillary article I wrote several years ago, but recently I decided to do some more research on it, and I have to admit, it’s a very interesting drug. Before I explain what it does, I think a discussion of some important hormones and enzymes are in order.

It is very interesting to see Dostinex aka cabergoline showing up in anabolic steroid forums and bodybuilding forums.  I have heard information regarding Dostinex being used in the "anti-aging" crowds but I have never spoken to any people in any of those groups about cabergoline.  I will be looking further in Dostinex / cabergoline usage in these areas in the near future.  I am also curious if college students are using cabergoline for the sexual health enhancements to impress their girlfriends.  I plan to interview some college students from the University of Georgia Athens (UGA) in regards to cabergoline use.

Cabergoline

Cabergoline is marketed primarily as Dostinex.  Cabergoline is a relatively new pharmaceutical that has enormous potential aiding male stamina. The most remarkable aspect of carbergoline aka Dostinex is that it has been found to substantially increase a man’s chances of sustaining multiple orgasms during sex. Many men on cabergoline have reported numerous multiple orgasms in rapid succession.

In one study of Cabergoline, sixty healthy male participants ages 22 to 31 on average needed a break of 19 minutes between lovemaking sessions. After taking Cabergoline they were able to have multiple orgasms within a few minutes. Medical psychologist Manfred Schedlowski was involved with the trials at Essen in Germany and stated that Cabergoline raised the libido to enable the male to orgasm again more quickly.

While Cabergoline aka Dostinex is known best for its sexual enhancement characteristics it has other uses as well.  Cabergoline (brand names Dostinex and Cabaser), an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. In vitro, rat studies show cabergoline has a direct inhibitory effect onpituitary lactotroph (prolactin) cells. It is frequently used as a first-line agent in the management of prolactinomas due to higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine.  In less technical jargon Cabergoline lower prolactin levels.  Excessive secretion of prolactin – which is known as hyperprolactinemia – is a relative common disorder in humans.  Common symptoms of hyperprolactinemia in women can include menstrual irregularities, and galactorrhea (which was covered in the preceding paragraph). Sadly, men who have hyperprolactinemia tend to have most of the same symptoms; enlarged mammary glands, milk production, and also have some other side effects to contend with, such as hypogonadism, decreased libido (sex drive), decreased sperm production and impotence

There are many uses for Cabergoline and we will cover them in upcoming posts in this blog.  Thank you for reading.